Literature-in-the-Loop: Citation-Grounded Triage for AI Protein Design

Quick answer: Lab-in-the-loop protein and antibody design generates tens of thousands of candidates per cycle but tests a few hundred. What lab-in-the-loop needs is literature-in-the-loop : a citation-grounded evidence-ranking step between generation and assay selection that retrieves published structures, affinities, homologous sequences, and negative results to rerank candidates, while…